Bartter syndrome, originally described by Bartter and colleagues in 1962, represents a set of closely related, renal tubular disorders characterized by hypokalemia, hypochloremia, metabolic alkalosis, and hyperreninemia with normal blood pressure. This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. The different types of Bartter syndrome are classified according to the age of onset, severity, and the specific gene that causes the condition. Treatment depends on the type of the syndrome present but chiefly focuses on restoring and maintaining the proper balance of fluids and electrolytes in the body.1
Cite this article:
Jyotika S. Kumar. Bartter Syndrome. Asian J. Nursing Education and Research. 2020; 10(4):509-511. doi: 10.5958/2349-2996.2020.00110.X
Jyotika S. Kumar. Bartter Syndrome. Asian J. Nursing Education and Research. 2020; 10(4):509-511. doi: 10.5958/2349-2996.2020.00110.X Available on: https://ajner.com/AbstractView.aspx?PID=2020-10-4-28
1. "Bartter syndrome: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 29 September 2019.
2. "Bartter Syndrome: Tubular and Cystic Kidney Disorders: Merck Manual Home Edition". Archived from the original on 4 January 2008. Retrieved 2007-12-31.
3. Rodriguez-Soriano J (1998). "Bartter and related syndromes: the puzzle is almostsolved". PediatrNephrol. 12 (4):315-27.
5. Naesens M, Steels P, Verberckmoes R, Vanrenterghem Y, Kuypers D (2004). "Bartter's and Gitelman's syndromes: from gene to clinic". Nephron Physiol. 96 (3): 65–78
6. Zaffanello M, Taranta A, Palma A, Bettinelli A, Marseglia GL, Emma F (2006). "Type IV Bartter syndrome: report of two new cases". Pediatr. Nephrol. 21 (6):766–70.
7. Vezzoli G, Arcidiacono T, Paloschi V, et al. (2006). "Autosomal dominant hypocalcemia with mild type 5 Bartter syndrome". J. Nephrol. 19 (4): 525–8.
8. Barter FC, Pronovr P, Gill JR, MacCardle RC (1962). "Hyperplasia of the juxtaglomerular complex with hyperaldostenorism and hypokalemic alkalosis. A new syndrome". Am J Med. 33 (6): 811-28. Reproduced in Barterr FC, Pronove P, Gill JR, MacCardle RC (1998). "Hyperplasia of the juxtaglomerular complex with hyperaldosteroneism and hypkalemic alkalosis. A new syndrome. 1962". J. Am. Soc. Nephrol. 9 (3): 516-28
9. Dane B, Yayla M, Dane C, Cetin A (2007). "Prenatal diagnosis of Bartter syndrome with biochemical examination of amniotic fluid: case report". Fetal Diagn. Ther. 22 (3): 206–8.