Author(s):
N. Dhanesh Kumar, E. Devakirubai
Email(s):
ddhanesh21@gmail.com , devajeba1974@gmail.com
DOI:
10.52711/2349-2996.2025.00022 
Address:
N. Dhanesh Kumar1, E. Devakirubai2
1Assistant Professor, Department of Medical Surgical Nursing, Sacred Heart Nursing College, Madurai.
2Principal and HOD of Medical Surgical Nursing, Sacred Heart Nursing College, Madurai.
*Corresponding Author
Published In:
Volume - 15,
Issue - 2,
Year - 2025
ABSTRACT:
Ewing tumors, also called Ewing sarcomas, are a class of malignancies that originate in the surrounding soft tissues or bones and have a few characteristics as common. Though they can appear in any age group, older kids and teenagers, it mostly affects adolescents. Ewing sarcoma (ES) is a highly metastatic form of sarcoma and the second most common primary malignant bone tumor. Previously linked to high rates of death even after trying treatments, significant developments in multi agent adjuvant chemotherapy and local therapy have significantly raised the 5-year survival rate from less than 20% to over 70%. But problems still exist, especially with regard to the recurrence rate. Prompt identification and intervention are essential to reduce the risks of morbidity and mortality rate associated with Ewing sarcoma.
Cite this article:
N. Dhanesh Kumar, E. Devakirubai. Ewing Sarcoma: The Fierce Tumor of Children. Asian Journal of Nursing Education and Research. 2025;15(2):101-5. doi: 10.52711/2349-2996.2025.00022
Cite(Electronic):
N. Dhanesh Kumar, E. Devakirubai. Ewing Sarcoma: The Fierce Tumor of Children. Asian Journal of Nursing Education and Research. 2025;15(2):101-5. doi: 10.52711/2349-2996.2025.00022 Available on: https://ajner.com/AbstractView.aspx?PID=2025-15-2-7
REFERENCES:
1. Types of Ewing tumors, Ewing Sarcoma Research and Statistics. (n.d.). American Cancer Society. https://www.cancer.org/cancer/types/ewing-tumor/about.html
2. Durer, S., Gasalberti, D. P., and Shaikh, H. (2024, January 8). Ewing Sarcoma. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559183/
3. Ewing sarcoma in adults. (2021, August 8). Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/sarcoma/ewingsarcoma - in adults #:~:text = Ewing % 20 sarcoma % 20 is % 2 0a % 20 type, include % 20 pain % 2 C % 20 swelling % 20 and % 20 fever.
4. Ludwig JA. Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future. Curr Opin Oncol. 2008 Jul; 20(4): 412-8.
5. Riggi N, Stamenkovic I. The Biology of Ewing sarcoma. Cancer Lett. 2007 Aug 28; 254(1):1-10.
6. Chakraborty, D., Rangamani, S., Kulothungan, V., Chaturvedi, M., Stephen, S., Das, P., Sudarshan, K. L., Surya, R. J., Kumar, K., John, A., Manoharan, N., Koyande, S., Swaminathan, R., Ramesh, C., Shrivastava, A., Ganesh, B., Mathur, P., and Nandakumar, A. Trends in incidence of Ewing sarcoma of bone in India – Evidence from the National Cancer Registry Programme (1982–2011). Journal of Bone Oncology. 2018; 12: 49–53. https://doi.org/10.1016/j.jbo.2018.04.002
7. Gaspar, N. et al. Ewing sarcoma: current management and future approaches through collaboration. J. Clin. Oncol. 2015; 33: 3036–3046.
8. Kim, S. K., and Park, Y. Ewing sarcoma: a chronicle of molecular pathogenesis. Human Pathology. 2016; 55: 91–100. https://doi.org/10.1016/j.humpath.2016.05.00
9. Ozaki T. Diagnosis and treatment of Ewing sarcoma of the bone: a review article. J Orthop Sci. 2015 Mar; 20(2): 250-63
10. Daecke, W., Ahrens, S., Juergens, H., Martini, A., Ewerbeck, V., Kotz, R., Winkelmann, W., and Bernd, L. Ewing?s sarcoma and primitive neuroectodermal tumor of hand and forearm. Journal of Cancer Research and Clinical Oncology. 2004; 131(4): 219–225. https://doi.org/10.1007/s00432-004-0637-9
11. Ross, K. A., Smyth, N. A., Murawski, C. D., and Kennedy, J. G. The Biology of Ewing Sarcoma. ISRN Oncology. 2013: 1–7. https://doi.org/10.1155/2013/759725
12. Biermann, J. S., Chow, W., Reed, D. R., Lucas, D., Adkins, D. R., Agulnik, M., Benjamin, R. S., Brigman, B., Budd, G. T., Curry, W. T., Didwania, A., Fabbri, N., Hornicek, F. J., Kuechle, J. B., Lindskog, D., Mayerson, J., McGarry, S. V., Million, L., Morris, C. D., Scavone, J. L. NCCN Guidelines Insights: Bone Cancer, Version 2.2017. Journal of the National Comprehensive Cancer Network. 2017; 15(2): 155–167. https://doi.org/10.6004/jnccn.2017.0017
13. Raciborska, A., Bilska, K., Rychłowska-Pruszyńska, M., Duczkowski, M., Duczkowska, A., Drabko, K., Chaber, R., Sobol, G., Wyrobek, E., Michalak, E., Rodriguez-Galindo, C., and Wożniak, W. Management and follow-up of Ewing sarcoma patients with isolated lung metastases. Journal of Pediatric Surgery. 2015; 51(7): 1067–1071. https://doi.org/10.1016/j.jpedsurg.2015.11.012
14. Biermann, J. S., Chow, W., Reed, D. R., Lucas, D., Adkins, D. R., Agulnik, M., Benjamin, R. S., Brigman, B., Budd, G. T., Curry, W. T., Didwania, A., Fabbri, N., Hornicek, F. J., Kuechle, J. B., Lindskog, D., Mayerson, J., McGarry, S. V., Million, L., Morris, C. D., . . . Scavone, J. L. NCCN Guidelines Insights: Bone Cancer, Version 2.2017. Journal of the National Comprehensive Cancer Network. 2017b; 15(2): 155–167. https://doi.org/10.6004/jnccn.2017.0017
15. Chodyla, M., Barbato, F., Dirksen, U., Kirchner, J., Schaarschmidt, B. M., Schweiger, B., Forsting, M., Herrmann, K., Umutlu, L., and Grueneisen, J. Utility of Integrated PET/MRI for the Primary Diagnostic Work-Up of Patients with Ewing Sarcoma: Preliminary Results. Diagnostics. 2022; 12(10): 2278. https://doi.org/10.3390/diagnostics12102278
16. Tumijan Wahidah, Muhammad Naeem Khattak, Nadiah Wan-Arfah, Nyi Naing. Five-year Survival of Osteosarcoma Patients in Hospital Universiti Sains Malaysia (HUSM): An Eleven Year Review. Research J. Pharm. and Tech. 2018; 11(8): 3534-3542
17. Kundan J. Tiwari, Komal Jadhav. Cancer is a Life-Threatening Disease: A Review. Res. J. Pharma. Dosage Forms and Tech. 2020; 12(2): 111-114.
18. S. Sneha Aishwarya, V. Gowri, D. Darling Chellathai. Honey a Therapeutic Trial in Osteosarcoma. Research J. Pharm. and Tech. 2019; 12(6): 2959-2962.